1 3732117123116Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others16Total37Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied Up to 12,924 European ancestry cases, up to 21,442 European ancestry controls; replicated in Up to 25,683 European ancestry cases, up to 17,015 European ancestry controls.
The effect
Each copy of the A allele carried 1.06 times the odds of Ulcerative colitis (95% confidence interval 1.017-1.096); p = 1 × 10−8.
How common The A allele had a frequency of about 29% in the people studied.
Where it sits Chromosome 11, band 11q21 — in an intron of MAML2.
What each result means
A/ATwo copies of the version the research linked to Ulcerative colitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Ulcerative colitis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Ulcerative colitis. This is the starting point the study compared everyone against.
rs483905 is a single position in the genome, in or near the MAML2 gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs483905 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs483905 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs483905 come from?
GWAS Catalog, Nature 2012, PMID:23128233. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 3732117123116Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others16Total37Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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