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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 32,532 European ancestry individuals.
The effect
The reported allele is A; the catalogue records no effect size
; p = 9 × 10−10.
Where it sits Chromosome 5, band 5q31.2 — in an intron of DNAJC18.
What each result means
A/ATwo copies of the version the research linked to Left ventricular ejection fraction. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Left ventricular ejection fraction. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Left ventricular ejection fraction. This is the starting point the study compared everyone against.
Science advances · 2023 · PMID 37126556 · open access
Questions about rs4835729
What is rs4835729?
rs4835729 is a single position in the genome, in or near the DNAJC18 gene. Published research associates it with left ventricular ejection fraction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4835729 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4835729 come from?
GWAS Catalog, Science advances 2023, PMID:37126556. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Left ventricular ejection fraction (rs4835729). MyGeneLog™. https://www.mygenelog.com/variants/rs4835729