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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 5,662 Pakistani ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0571 lower (95% confidence interval 0.04-0.074); p = 2 × 10−11.
Where it sits Chromosome 4, band 4q26 — between genes, 25.7 kb from UGT8.
What each result means
A/ANo copy of the version the research linked to Phosphatidylglycerol(32:1)_[M+OAc]1- levels. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Phosphatidylglycerol(32:1)_[M+OAc]1- levels. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Phosphatidylglycerol(32:1)_[M+OAc]1- levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs4834421 is a single position in the genome, in or near the near UGT8 gene. Published research associates it with phosphatidylglycerol(32:1)_[m+oac]1- levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4834421 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4834421 come from?
GWAS Catalog, BMC medicine 2021, PMID:34503513. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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