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Corpus callosum total area

near GAP43 · rs4831182

What the study found

Who was studied 46,685 European ancestry individuals; replicated in 4,765 non-European ancestry individuals.

The effect Each copy of the A allele shifted the measure 2.87 lower (95% confidence interval 1.95-3.8); p = 1 × 10−9.

How common The A allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 3, band 3q13.31 — between genes, 116.7 kb from EIF4E2P2.

What each result means

A/A Two copies of the version the research linked to Corpus callosum total area. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Corpus callosum total area. That is a smaller link than two copies.
G/G No copy of the version the research linked to Corpus callosum total area. This is the starting point the study compared everyone against.
Source

Questions about rs4831182

What is rs4831182?

rs4831182 is a single position in the genome, in or near the near GAP43 gene. Published research associates it with corpus callosum total area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4831182 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4831182 come from?

GWAS Catalog, Nature communications 2025, PMID:41188267. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Corpus callosum total area (rs4831182). MyGeneLog™. https://www.mygenelog.com/variants/rs4831182

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