Sensitive

Prostate cancer

FGD1 · rs4826594

Where this position leads

Condition: Prostate Cancer

rs4826594 Condition: Prostate Cancer Prostate Cancer Condition rs4826594 rs4826594 FGD1

What the study found

Who was studied 5,088 Japanese ancestry cases, 10,682 Japanese ancestry controls; replicated in 4,818 Japanese ancestry cases, 73,261 Japanese ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 7 × 10−9.

How common The A allele had a frequency of about 51% in the people studied.

Where it sits Chromosome X, band Xp11.22 — between genes, 12.4 kb from TSR2.

What each result means

A/A Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
G/G No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
Source

Questions about rs4826594

What is rs4826594?

rs4826594 is a single position in the genome, in or near the FGD1 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4826594 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs4826594 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4826594 come from?

GWAS Catalog, Nature communications 2019, PMID:31562322. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer (rs4826594). MyGeneLog™. https://www.mygenelog.com/variants/rs4826594

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