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Axial length

ZNRF3 · rs4823003

What the study found

Who was studied 33,483 Japanese ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.058 lower (95% confidence interval 0.04-0.076); p = 8 × 10−11.

How common The C allele had a frequency of about 60% in the people studied.

Where it sits Chromosome 22, band 22q12.1 — in an intron of ZNRF3.

What each result means

A/A No copy of the version the research linked to Axial length. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Axial length. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Axial length. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4823003

What is rs4823003?

rs4823003 is a single position in the genome, in or near the ZNRF3 gene. Published research associates it with axial length. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4823003 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4823003 come from?

GWAS Catalog, Ophthalmology science 2022, PMID:36246171. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Axial length (rs4823003). MyGeneLog™. https://www.mygenelog.com/variants/rs4823003

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