Standard

Red blood cell erythrocyte distribution width (UKB data field 30070)

HSPA1L · rs481825

Where this position leads

Condition: Celiac Disease

rs481825 Condition: Celiac Disease Celiac Disease Condition rs481825 rs481825 HSPA1L

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0362 higher (95% confidence interval 0.026-0.046); p = 5 × 10−13.

How common The A allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — in an intron of HSPA1L.

What each result means

A/A Two copies of the version the research linked to Red blood cell erythrocyte distribution width (UKB data field 30070). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Red blood cell erythrocyte distribution width (UKB data field 30070). That is a smaller link than two copies.
C/C No copy of the version the research linked to Red blood cell erythrocyte distribution width (UKB data field 30070). This is the starting point the study compared everyone against.
Source

Questions about rs481825

What is rs481825?

rs481825 is a single position in the genome, in or near the HSPA1L gene. Published research associates it with red blood cell erythrocyte distribution width (ukb data field 30070). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs481825 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs481825 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs481825 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Red blood cell erythrocyte distribution width (UKB data field 30070) (rs481825). MyGeneLog™. https://www.mygenelog.com/variants/rs481825

← See all variants