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IL10RB protein levels

near LINC01548 · rs4817537

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0613 lower (95% confidence interval 0.046-0.077); p = 4 × 10−17.

How common The A allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 21, band 21q22.11 — between genes, 24.1 kb from LINC01548.

What each result means

A/A Two copies of the version the research linked to IL10RB protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to IL10RB protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to IL10RB protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs4817537

What is rs4817537?

rs4817537 is a single position in the genome, in or near the near LINC01548 gene. Published research associates it with il10rb protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4817537 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4817537 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

IL10RB protein levels (rs4817537). MyGeneLog™. https://www.mygenelog.com/variants/rs4817537

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