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Phosphatidylglycerol (36:2) levels

ABHD12 · rs4815412

What the study found

Who was studied 4,492 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.143 higher (95% confidence interval 0.1-0.186); p = 2 × 10−10.

Where it sits Chromosome 20, band 20p11.21 — in an intron of ABHD12.

What each result means

A/A Two copies of the version the research linked to Phosphatidylglycerol (36:2) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Phosphatidylglycerol (36:2) levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Phosphatidylglycerol (36:2) levels. This is the starting point the study compared everyone against.
Source

Questions about rs4815412

What is rs4815412?

rs4815412 is a single position in the genome, in or near the ABHD12 gene. Published research associates it with phosphatidylglycerol (36:2) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4815412 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4815412 come from?

GWAS Catalog, Nature communications 2022, PMID:35668104. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Phosphatidylglycerol (36:2) levels (rs4815412). MyGeneLog™. https://www.mygenelog.com/variants/rs4815412

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