1 2121315Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others15Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 343,621 European ancestry individuals, 72,866 East Asian ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0172 higher (95% confidence interval 0.012-0.022); p = 3 × 10−11.
Where it sits Chromosome 19, band 19p13.11 — in an intron of PDE4C.
What each result means
C/CNo copy of the version the research linked to LDL cholesterol. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to LDL cholesterol. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to LDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs4808765 is a single position in the genome, in or near the PDE4C gene. Published research associates it with ldl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4808765 linked to?
On MyGeneLog this position is linked to Colon Polyp, Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs4808765 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4808765 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 2121315Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others15Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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