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Urokinase-type plasminogen activator levels

CHST9 · rs4800787

What the study found

Who was studied 14,734 European ancestry individuals; replicated in 1,585 European or unknown ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.094 lower (95% confidence interval 0.069-0.119); p = 6 × 10−14.

How common The T allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 18, band 18q11.2 — in an intron of CHST9.

What each result means

C/C No copy of the version the research linked to Urokinase-type plasminogen activator levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Urokinase-type plasminogen activator levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Urokinase-type plasminogen activator levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4800787

What is rs4800787?

rs4800787 is a single position in the genome, in or near the CHST9 gene. Published research associates it with urokinase-type plasminogen activator levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4800787 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4800787 come from?

GWAS Catalog, Nature immunology 2023, PMID:37563310. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urokinase-type plasminogen activator levels (rs4800787). MyGeneLog™. https://www.mygenelog.com/variants/rs4800787

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