Standard

Psoriasis

NOS2 · rs4795067

Where this position leads

Condition: Psoriasis

rs4795067 Condition: Psoriasis Psoriasis Condition rs4795067 rs4795067 NOS2

What the study found

Who was studied Up to 1,831 cases, up to 2,546 controls; replicated in Up to 4,064 cases, up to 4,685 controls.

The effect Each copy of the G allele carried 1.19 times the odds of Psoriasis; p = 4 × 10−11.

How common The G allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 17, band 17q11.2 — in an intron of NOS2.

What each result means

A/A No copy of the version the research linked to Psoriasis. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Psoriasis. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Psoriasis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs4795067

What is rs4795067?

rs4795067 is a single position in the genome, in or near the NOS2 gene. Published research associates it with psoriasis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4795067 linked to?

On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs4795067?

Subjects that appear in the title or abstract of the same papers as this rsID include cholesterol and blood fats (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs4795067 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4795067 come from?

GWAS Catalog, Nat Genet 2010, PMID:20953189. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Psoriasis (rs4795067). MyGeneLog™. https://www.mygenelog.com/variants/rs4795067

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