Standard

Systolic blood pressure

near ADAM11 · rs4793146

Where this position leads

Condition: Blood Pressure

rs4793146 Condition: Blood Pressure Blood Pressure Condition rs4793146 rs4793146 near ADAM11

What the study found

Who was studied 526,001 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.394 lower (95% confidence interval 0.27-0.52); p = 2 × 10−10.

Where it sits Chromosome 17, band 17q21.31 — between genes, 0.2 kb from ADAM11.

What each result means

A/A Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
C/C No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs4793146

What is rs4793146?

rs4793146 is a single position in the genome, in or near the near ADAM11 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4793146 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs4793146 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4793146 come from?

GWAS Catalog, Investigative ophthalmology & visual science 2022, PMID:35762941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs4793146). MyGeneLog™. https://www.mygenelog.com/variants/rs4793146

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