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FEV1/FVC ratio

DNAH2 · rs4791806

Where this position leads

Condition: Pulmonary Function (Lung Capacity)

rs4791806 Condition: Pulmonary Function (Lung Capacity) Pulmonary Function (Lung Capacity) Condition rs4791806 rs4791806 DNAH2

What the study found

Who was studied 129,680 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0275 higher (95% confidence interval 0.018-0.037); p = 3 × 10−8.

Where it sits Chromosome 17, band 17p13.1 — in an intron of DNAH2.

What each result means

A/A No copy of the version the research linked to FEV1/FVC ratio. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to FEV1/FVC ratio. That is a smaller link than two copies.
G/G Two copies of the version the research linked to FEV1/FVC ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4791806

What is rs4791806?

rs4791806 is a single position in the genome, in or near the DNAH2 gene. Published research associates it with fev1/fvc ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4791806 linked to?

On MyGeneLog this position is linked to Pulmonary Function (Lung Capacity). The research behind each link, and its sources, are set out on that condition page.

Does having rs4791806 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4791806 come from?

GWAS Catalog, Nature genetics 2026, PMID:41565855. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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FEV1/FVC ratio (rs4791806). MyGeneLog™. https://www.mygenelog.com/variants/rs4791806

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