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Linoleic acid percentage of total fatty acids

GRB2 · rs4789182

What the study found

Who was studied 199,732 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.021 higher (95% confidence interval 0.014-0.028); p = 1 × 10−9.

How common The G allele had a frequency of about 27% in the people studied.

Where it sits Chromosome 17, band 17q25.1 — in an intron of GRB2.

What each result means

A/A No copy of the version the research linked to Linoleic acid percentage of total fatty acids. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Linoleic acid percentage of total fatty acids. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Linoleic acid percentage of total fatty acids. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4789182

What is rs4789182?

rs4789182 is a single position in the genome, in or near the GRB2 gene. Published research associates it with linoleic acid percentage of total fatty acids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4789182 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4789182 come from?

GWAS Catalog, British journal of cancer 2025, PMID:40307439. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Linoleic acid percentage of total fatty acids (rs4789182). MyGeneLog™. https://www.mygenelog.com/variants/rs4789182

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