Sensitive

Type 1 diabetes

IL27 · rs4788084

Where this position leads

Condition: Type 1 Diabetes

rs4788084 Condition: Type 1 Diabetes Type 1 Diabetes Condition rs4788084 rs4788084 IL27

What the study found

Who was studied 8,506 European ancestry cases, up to 10,596 European ancestry controls.

The effect Each copy of the C allele carried 1.15 times the odds of Type 1 diabetes; p = 1 × 10−8.

Where it sits Chromosome 16, band 16p11.2 — between genes, 4.2 kb from NUPR1.

What each result means

C/C Two copies of the version the research linked to Type 1 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Type 1 diabetes. That is a smaller link than two copies.
T/T No copy of the version the research linked to Type 1 diabetes. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs4788084

What is rs4788084?

rs4788084 is a single position in the genome, in or near the IL27 gene. Published research associates it with type 1 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4788084 linked to?

On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs4788084?

Subjects that appear in the title or abstract of the same papers as this rsID include liver (1 papers), brain and memory (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs4788084 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4788084 come from?

GWAS Catalog, PLoS Genet 2011, PMID:21829393. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 1 diabetes (rs4788084). MyGeneLog™. https://www.mygenelog.com/variants/rs4788084

← See all variants