Sensitive

Cancer (pleiotropy)

GAS8 · rs4785767

What the study found

Who was studied 64,962 European ancestry cases, 410,350 European ancestry controls.

The effect Each copy of the T allele carried 0.91 times the odds of Cancer (pleiotropy) (95% confidence interval 0.88-0.931); p = 2 × 10−12.

Where it sits Chromosome 16, band 16q24.3 — in a non-coding transcript of GAS8.

What each result means

C/C No copy of the version the research linked to Cancer (pleiotropy). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Cancer (pleiotropy). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Cancer (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4785767

What is rs4785767?

rs4785767 is a single position in the genome, in or near the GAS8 gene. Published research associates it with cancer (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4785767 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4785767 come from?

GWAS Catalog, Nature communications 2020, PMID:32887889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Cancer (pleiotropy) (rs4785767). MyGeneLog™. https://www.mygenelog.com/variants/rs4785767

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