Standard
Low tan response
near DEF8 · rs4785752
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Low tan response compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Low tan response.
G/G
Published research associates this genotype with typical/baseline likelihood of Low tan response — no copies of the reported risk allele.
Source
Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure
Visconti A,
Duffy DL,
Liu F,
Zhu G,
Wu W,
Chen Y,
Hysi PG,
Zeng C,
Sanna M,
Iles MM,
Kanetsky PA,
Demenais F
and 10 more — show all
Nature communications · 2018 · PMID 29739929 · open access
Questions about rs4785752
What is rs4785752?
rs4785752 is a single position in the genome, in or near the near DEF8 gene. Published research associates it with low tan response. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4785752 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4785752 come from?
GWAS Catalog, Nat Commun 2018, PMID:29739929. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants