Standard

Body mass index

near RNU6-1 · rs4776990

Where this position leads

Condition: Childhood Body Mass Index

rs4776990 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs4776990 rs4776990 near RNU6-1

What the study found

Who was studied 195,070 Taiwanese ancestry, Japanese ancestry individuals, 334,487 European ancestry, Latino, East Asian ancestry, African American, South Asian ancestry individuals, 361,194 individuals.

The effect Each copy of the C allele shifted the measure 0.0283 lower (95% confidence interval 0.022-0.034); p = 1 × 10−21.

How common The C allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 15, band 15q23 — between genes, 5 kb from RNU6-1.

What each result means

C/C Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs4776990

What is rs4776990?

rs4776990 is a single position in the genome, in or near the near RNU6-1 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4776990 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs4776990 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4776990 come from?

GWAS Catalog, PLoS genetics 2022, PMID:35051171. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs4776990). MyGeneLog™. https://www.mygenelog.com/variants/rs4776990

← See all variants