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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,602 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0493 higher (95% confidence interval 0.043-0.055); p = 2 × 10−57.
Where it sits Chromosome 15, band 15q22.2 — inside RPS27L.
What each result means
A/ATwo copies of the version the research linked to Cerebrospinal fluid succinylcarnitine (C4-DC) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Cerebrospinal fluid succinylcarnitine (C4-DC) levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Cerebrospinal fluid succinylcarnitine (C4-DC) levels. This is the starting point the study compared everyone against.
rs4774478 is a single position in the genome, in or near the RPS27L gene. Published research associates it with cerebrospinal fluid succinylcarnitine (c4-dc) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4774478 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4774478 come from?
GWAS Catalog, Nature genetics 2024, PMID:39528826. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 624Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others4Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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