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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,145 Central Asian ancestry cases, 2,027 Central Asian ancestry controls, 4,630 European ancestry cases, 373,345 European ancestry controls; replicated in 452 Kazakh ancestry cases, 361 Kazakh ancestry controls, 580 European ancestry cases, 760 European ancestry controls.
The effect
Each copy of the C allele carried 1.19 times the odds of Preeclampsia (fetal genotype effect) (95% confidence interval 1.13-1.24); p = 4 × 10−14.
How common The C allele had a frequency of about 52% in the people studied.
Where it sits Chromosome 13, band 13q12.3 — between genes, 34.5 kb from EIF4A1P7.
What each result means
C/CTwo copies of the version the research linked to Preeclampsia (fetal genotype effect). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Preeclampsia (fetal genotype effect). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Preeclampsia (fetal genotype effect). This is the starting point the study compared everyone against.
Nature communications · 2020 · PMID 33239696 · open access
Questions about rs4769612
What is rs4769612?
rs4769612 is a single position in the genome, in or near the near EIF4A1P7 gene. Published research associates it with preeclampsia (fetal genotype effect). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4769612 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4769612 come from?
GWAS Catalog, Nature communications 2020, PMID:33239696. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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