0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 3,128 East Asian ancestry cases, 5,493 East Asian ancestry controls.
The effect
Each copy of the A allele carried 1.29 times the odds of Neovascular age-related macular degeneration (95% confidence interval 1.19-1.39); p = 2 × 10−10.
How common The A allele had a frequency of about 74% in the people studied.
Where it sits Chromosome 13, band 13q12.12 — in an intron of SPATA13.
What each result means
A/ATwo copies of the version the research linked to Neovascular age-related macular degeneration. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Neovascular age-related macular degeneration. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Neovascular age-related macular degeneration. This is the starting point the study compared everyone against.
Nature communications · 2023 · PMID 37696869 · open access
Questions about rs4769312
What is rs4769312?
rs4769312 is a single position in the genome, in or near the SPATA13 gene. Published research associates it with neovascular age-related macular degeneration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4769312 linked to?
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
Does having rs4769312 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4769312 come from?
GWAS Catalog, Nature communications 2023, PMID:37696869. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.