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Insomnia

KSR2 · rs4767645

Where this position leads

Condition: Insomnia

rs4767645 Condition: Insomnia Insomnia Condition rs4767645 rs4767645 KSR2

What the study found

Who was studied 651,923 European ancestry males, 679,087 European ancestry females.

The effect Each copy of the G allele carried 1.04 times the odds of Insomnia (95% confidence interval 1.03-1.05); p = 6 × 10−10.

How common The G allele had a frequency of about 54% in the people studied.

Where it sits Chromosome 12, band 12q24.23 — in an intron of KSR2.

What each result means

G/G Two copies of the version the research linked to Insomnia. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Insomnia. That is a smaller link than two copies.
T/T No copy of the version the research linked to Insomnia. This is the starting point the study compared everyone against.
Source

Questions about rs4767645

What is rs4767645?

rs4767645 is a single position in the genome, in or near the KSR2 gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4767645 linked to?

On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.

Does having rs4767645 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4767645 come from?

GWAS Catalog, Nature genetics 2019, PMID:30804565. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insomnia (rs4767645). MyGeneLog™. https://www.mygenelog.com/variants/rs4767645

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