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Sleep duration

KSR2 · rs4767550

Where this position leads

Condition: Sleep and Circadian Rhythm

rs4767550 Condition: Sleep and Circadian Rhythm Sleep and Circadian Rhythm Condition rs4767550 rs4767550 KSR2

What the study found

Who was studied 446,118 European ancestry individuals; replicated in 47,180 adults, 10,554 children or adolescents.

The effect Each copy of the G allele shifted the measure 0.822 higher; p = 1 × 10−10.

Where it sits Chromosome 12, band 12q24.22 — in an intron of KSR2.

What each result means

A/A No copy of the version the research linked to Sleep duration. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Sleep duration. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Sleep duration. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4767550

What is rs4767550?

rs4767550 is a single position in the genome, in or near the KSR2 gene. Published research associates it with sleep duration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4767550 linked to?

On MyGeneLog this position is linked to Sleep and Circadian Rhythm. The research behind each link, and its sources, are set out on that condition page.

Does having rs4767550 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4767550 come from?

GWAS Catalog, Nature communications 2019, PMID:30846698. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sleep duration (rs4767550). MyGeneLog™. https://www.mygenelog.com/variants/rs4767550

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