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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 274,251 British ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.335 higher (95% confidence interval 0.26-0.41); p = 1 × 10−17.
Where it sits Chromosome 12, band 12q24.11 — in an intron of CUX2.
What each result means
C/CNo copy of the version the research linked to Creatinine-cystatin C ratio. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Creatinine-cystatin C ratio. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Creatinine-cystatin C ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Frontiers in endocrinology · 2024 · PMID 38836225 · open access
Questions about rs4766453
What is rs4766453?
rs4766453 is a single position in the genome, in or near the CUX2 gene. Published research associates it with creatinine-cystatin c ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4766453 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4766453 come from?
GWAS Catalog, Frontiers in endocrinology 2024, PMID:38836225. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Creatinine-cystatin C ratio (rs4766453). MyGeneLog™. https://www.mygenelog.com/variants/rs4766453