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Right hippocampal volume

MSRB3 · rs4762080

What the study found

Who was studied 65,791 European ancestry, East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0535 higher (95% confidence interval 0.041-0.066); p = 4 × 10−16.

How common The A allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 12, band 12q14.3 — in an intron of MSRB3.

What each result means

A/A Two copies of the version the research linked to Right hippocampal volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Right hippocampal volume. That is a smaller link than two copies.
T/T No copy of the version the research linked to Right hippocampal volume. This is the starting point the study compared everyone against.
Source

Questions about rs4762080

What is rs4762080?

rs4762080 is a single position in the genome, in or near the MSRB3 gene. Published research associates it with right hippocampal volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4762080 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4762080 come from?

GWAS Catalog, Nature genetics 2023, PMID:37337106. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Right hippocampal volume (rs4762080). MyGeneLog™. https://www.mygenelog.com/variants/rs4762080

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