Standard

Sum neutrophil eosinophil counts

near LYZ · rs4761234

Where this position leads

Condition: Blood Cell Counts

rs4761234 Condition: Blood Cell Counts Blood Cell Counts Condition rs4761234 rs4761234 near LYZ

What the study found

Who was studied 170,384 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0221 higher (95% confidence interval 0.015-0.029); p = 8 × 10−10.

How common The C allele had a frequency of about 49% in the people studied.

Where it sits Chromosome 12, band 12q15 — between genes, 10.1 kb from LYZ.

What each result means

C/C Two copies of the version the research linked to Sum neutrophil eosinophil counts. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Sum neutrophil eosinophil counts. That is a smaller link than two copies.
T/T No copy of the version the research linked to Sum neutrophil eosinophil counts. This is the starting point the study compared everyone against.
Source

Questions about rs4761234

What is rs4761234?

rs4761234 is a single position in the genome, in or near the near LYZ gene. Published research associates it with sum neutrophil eosinophil counts. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4761234 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs4761234 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4761234 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sum neutrophil eosinophil counts (rs4761234). MyGeneLog™. https://www.mygenelog.com/variants/rs4761234

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