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Birth weight (winsorised)

near PARVA · rs4757634

Where this position leads

Condition: Birth Weight

rs4757634 Condition: Birth Weight Birth Weight Condition rs4757634 rs4757634 near PARVA

What the study found

Who was studied 241,168 British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.00866 kg lower (95% confidence interval 0.0056-0.0117); p = 2 × 10−8.

Where it sits Chromosome 11, band 11p15.3 — between genes, 40 kb from PARVA.

What each result means

A/A Two copies of the version the research linked to Birth weight (winsorised). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Birth weight (winsorised). That is a smaller link than two copies.
G/G No copy of the version the research linked to Birth weight (winsorised). This is the starting point the study compared everyone against.
Source

Questions about rs4757634

What is rs4757634?

rs4757634 is a single position in the genome, in or near the near PARVA gene. Published research associates it with birth weight (winsorised). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4757634 linked to?

On MyGeneLog this position is linked to Birth Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs4757634 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4757634 come from?

GWAS Catalog, Diabetologia 2025, PMID:40210729. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Birth weight (winsorised) (rs4757634). MyGeneLog™. https://www.mygenelog.com/variants/rs4757634

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