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Cardiac MRI latent phenotype (Z26_S3)

ALX4 · rs4755800

What the study found

Who was studied 47,740 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0398 lower (95% confidence interval 0.028-0.052); p = 2 × 10−10.

Where it sits Chromosome 11, band 11p11.2 — in an intron of ALX4.

What each result means

A/A Two copies of the version the research linked to Cardiac MRI latent phenotype (Z26_S3). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cardiac MRI latent phenotype (Z26_S3). That is a smaller link than two copies.
G/G No copy of the version the research linked to Cardiac MRI latent phenotype (Z26_S3). This is the starting point the study compared everyone against.
Source

Questions about rs4755800

What is rs4755800?

rs4755800 is a single position in the genome, in or near the ALX4 gene. Published research associates it with cardiac mri latent phenotype (z26_s3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4755800 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4755800 come from?

GWAS Catalog, Nature communications 2026, PMID:42373625. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Cardiac MRI latent phenotype (Z26_S3) (rs4755800). MyGeneLog™. https://www.mygenelog.com/variants/rs4755800

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