0 110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 5,705 European ancestry cases, 7,067 European ancestry controls.
The effect
Each copy of the G allele carried 0.68 times the odds of Alzheimer's disease (95% confidence interval 0.601-0.774); p = 3 × 10−9.
How common The G allele had a frequency of about 21% in the people studied.
Where it sits Chromosome 10, band 10p12.33 — in an intron of MRC1.
What each result means
A/ANo copy of the version the research linked to Alzheimer's disease. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Alzheimer's disease. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Frontiers in aging neuroscience · 2021 · PMID 34122051 · open access
Questions about rs4748424
What is rs4748424?
rs4748424 is a single position in the genome, in or near the MRC1 gene. Published research associates it with alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4748424 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease Risk (APOE). The research behind each link, and its sources, are set out on that condition page.
Does having rs4748424 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4748424 come from?
GWAS Catalog, Frontiers in aging neuroscience 2021, PMID:34122051. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.