Standard

Body mass index

LRMDA · rs4746339

Where this position leads

Condition: Childhood Body Mass Index

rs4746339 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs4746339 rs4746339 LRMDA

What the study found

Who was studied 806,834 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0131 lower (95% confidence interval 0.0094-0.0168); p = 1 × 10−11.

How common The A allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 10, band 10q22.2 — in an intron of LRMDA.

What each result means

A/A Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs4746339

What is rs4746339?

rs4746339 is a single position in the genome, in or near the LRMDA gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4746339 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs4746339 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4746339 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs4746339). MyGeneLog™. https://www.mygenelog.com/variants/rs4746339

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