Who was studied 257,841 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0183 higher (95% confidence interval 0.012-0.024); p = 9 × 10−10.
How common The A allele had a frequency of about 34% in the people studied.
Where it sits Chromosome 9, band 9q22.31 — in an intron of FAM120A.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cognitive performance compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cognitive performance.
G/GPublished research associates this genotype with typical/baseline likelihood of Cognitive performance — no copies of the reported risk allele.
rs4744250 is a single position in the genome, in or near the FAM120A gene. Published research associates it with cognitive performance. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4744250 linked to?
On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.
Does having rs4744250 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4744250 come from?
GWAS Catalog, Nat Genet 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0
18
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.