Standard
Diffuse large B cell lymphoma
MYC · rs4733601
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Diffuse large B cell lymphoma compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Diffuse large B cell lymphoma.
G/G
Published research associates this genotype with typical/baseline likelihood of Diffuse large B cell lymphoma — no copies of the reported risk allele.
Source
Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma
Cerhan JR,
Berndt SI,
Vijai J,
Ghesquières H,
McKay J,
Wang SS,
Wang Z,
Yeager M,
Conde L,
de Bakker PI,
Nieters A,
Cox D
and 110 more — show all
Burdett L,
Monnereau A,
Flowers CR,
De Roos AJ,
Brooks-Wilson AR,
Lan Q,
Severi G,
Melbye M,
Gu J,
Jackson RD,
Kane E,
Teras LR,
Purdue MP,
Vajdic CM,
Spinelli JJ,
Giles GG,
Albanes D,
Kelly RS,
Zucca M,
Bertrand KA,
Zeleniuch-Jacquotte A,
Lawrence C,
Hutchinson A,
Zhi D,
Habermann TM,
Link BK,
Novak AJ,
Dogan A,
Asmann YW,
Liebow M,
Thompson CA,
Ansell SM,
Witzig TE,
Weiner GJ,
Veron AS,
Zelenika D,
Tilly H,
Haioun C,
Molina TJ,
Hjalgrim H,
Glimelius B,
Adami HO,
Bracci PM,
Riby J,
Smith MT,
Holly EA,
Cozen W,
Hartge P,
Morton LM,
Severson RK,
Tinker LF,
North KE,
Becker N,
Benavente Y,
Boffetta P,
Brennan P,
Foretova L,
Maynadie M,
Staines A,
Lightfoot T,
Crouch S,
Smith A,
Roman E,
Diver WR,
Offit K,
Zelenetz A,
Klein RJ,
Villano DJ,
Zheng T,
Zhang Y,
Holford TR,
Kricker A,
Turner J,
Southey MC,
Clavel J,
Virtamo J,
Weinstein S,
Riboli E,
Vineis P,
Kaaks R,
Trichopoulos D,
Vermeulen RC,
Boeing H,
Tjonneland A,
Angelucci E,
Di Lollo S,
Rais M,
Birmann BM,
Laden F,
Giovannucci E,
Kraft P,
Huang J,
Ma B,
Ye Y,
Chiu BC,
Sampson J,
Liang L,
Park JH,
Chung CC,
Weisenburger DD,
Chatterjee N,
Fraumeni JF Jr,
Slager SL,
Wu X,
de Sanjose S,
Smedby KE,
Salles G,
Skibola CF,
Rothman N,
Chanock SJ
Nature genetics · 2014 · PMID 25261932 · open access
Questions about rs4733601
What is rs4733601?
rs4733601 is a single position in the genome, in or near the MYC gene. Published research associates it with diffuse large b cell lymphoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4733601 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4733601 come from?
GWAS Catalog, Nat Genet 2014, PMID:25261932. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants