3 5542634222228Reads by AI crawlersClaude4ChatGPT2Google · Gemini6Perplexity3Meta AI4Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others28Total55Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 6,687 European ancestry cases, 19,718 European ancestry controls; replicated in 9,628 European ancestry cases, 12,917 European ancestry controls.
The effect
Each copy of the A allele carried 1.07 times the odds of Ulcerative colitis (95% confidence interval 1.03-1.11); p = 2 × 10−8.
How common The A allele had a frequency of about 44% in the people studied.
Where it sits Chromosome 7, band 7q32.1 — inside IRF5.
What each result means
A/ATwo copies of the version the research linked to Ulcerative colitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Ulcerative colitis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Ulcerative colitis. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs4728142
What is rs4728142?
rs4728142 is a single position in the genome, in or near the TNPO3 gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4728142 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs4728142?
Subjects that appear in the title or abstract of the same papers as this rsID include allergies (1 papers), liver (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs4728142 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4728142 come from?
GWAS Catalog, Nat Genet 2011, PMID:21297633. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 5542634222228Reads by AI crawlersClaude4ChatGPT2Google · Gemini6Perplexity3Meta AI4Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others28Total55Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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