Standard

C->U-editing enzyme APOBEC-2 levels

OARD1 · rs4714422

What the study found

Who was studied 2,549 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.269 lower (95% confidence interval 0.21-0.33); p = 1 × 10−14.

How common The G allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 6, band 6p21.1 — inside OARD1.

What each result means

A/A No copy of the version the research linked to C->U-editing enzyme APOBEC-2 levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to C->U-editing enzyme APOBEC-2 levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to C->U-editing enzyme APOBEC-2 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4714422

What is rs4714422?

rs4714422 is a single position in the genome, in or near the OARD1 gene. Published research associates it with c->u-editing enzyme apobec-2 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4714422 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4714422 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

C->U-editing enzyme APOBEC-2 levels (rs4714422). MyGeneLog™. https://www.mygenelog.com/variants/rs4714422

← See all variants