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Who was studied 18,900 European ancestry cases, 1,472 Japanese ancestry cases, 422 African American cases, 300 Latino cases, 305 cases, 84,166 European ancestry controls, 7,966 Japanese ancestry controls, 844 African American controls, 1,592 Latino controls, 896 controls; replicated in 30,588 European ancestry cases, 459 African American cases, 1,012 Chinese ancestry cases, 226,537 European ancestry controls, 729 African American controls, 1,362 Chinese ancestry controls.
The effect
Each copy of the G allele carried 1.10 times the odds of Atopic dermatitis (95% confidence interval -); p = 5 × 10−9.
How common The G allele had a frequency of about 73% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — between genes, 17.9 kb from HLA-DRB1.
What each result means
G/GTwo copies of the version the research linked to Atopic dermatitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Atopic dermatitis. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Atopic dermatitis. This is the starting point the study compared everyone against.
Nature genetics · 2015 · PMID 26482879 · open access
Questions about rs4713555
What is rs4713555?
rs4713555 is a single position in the genome, in or near the HLA-DRB1 gene. Published research associates it with atopic dermatitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4713555 linked to?
On MyGeneLog this position is linked to Atopic Dermatitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs4713555 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4713555 come from?
GWAS Catalog, Nat Genet 2015, PMID:26482879. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 423323222124Reads by AI crawlersClaude3ChatGPT3Google · Gemini0Perplexity2Meta AI3Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others24Total42Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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