Sensitive

Parkinson's disease-related grey matter volume atrophy

MBP · rs470934

Where this position leads

Condition: Parkinson's Disease

rs470934 Condition: Parkinson's Disease Parkinson's Disease Condition rs470934 rs470934 MBP

What the study found

Who was studied 35,098 European ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 1 × 10−8.

Where it sits Chromosome 18, band 18q23 — in an intron of MBP.

What each result means

G/G No copy of the version the research linked to Parkinson's disease-related grey matter volume atrophy. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Parkinson's disease-related grey matter volume atrophy. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Parkinson's disease-related grey matter volume atrophy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs470934

What is rs470934?

rs470934 is a single position in the genome, in or near the MBP gene. Published research associates it with parkinson's disease-related grey matter volume atrophy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs470934 linked to?

On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs470934 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs470934 come from?

GWAS Catalog, NeuroImage 2026, PMID:42336304. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Parkinson's disease-related grey matter volume atrophy (rs470934). MyGeneLog™. https://www.mygenelog.com/variants/rs470934

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