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Body mass index

CERT1 · rs4704219

Where this position leads

Conditions: Obesity and Body Weight, Childhood Body Mass Index

rs4704219 Condition: Obesity and Body Weight Obesity and Body Weight Condition Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs4704219 rs4704219 CERT1

What the study found

Who was studied 441,761 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0246 higher (95% confidence interval 0.021-0.028); p = 3 × 10−36.

Where it sits Chromosome 5, band 5q13.3 — in an intron of CERT1.

What each result means

C/C Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs4704219

What is rs4704219?

rs4704219 is a single position in the genome, in or near the CERT1 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4704219 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight, Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs4704219 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4704219 come from?

GWAS Catalog, Diabetologia 2023, PMID:37280435. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs4704219). MyGeneLog™. https://www.mygenelog.com/variants/rs4704219

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