Standard
Drinks per week
near PCNAP1 · rs4699726
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 121,859 East Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.055 higher (95% confidence interval 0.047-0.063); p = 2 × 10−38.
How common The C allele had a frequency of about 22% in the people studied.
Where it sits Chromosome 4, band 4q23 — between genes, 16.7 kb from PCNAP1.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Drinks per week compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Drinks per week.
T/T
Published research associates this genotype with typical/baseline likelihood of Drinks per week — no copies of the reported risk allele.
Source
Genetic diversity fuels gene discovery for tobacco and alcohol use
Saunders GRB,
Wang X,
Chen F,
Jang SK,
Liu M,
Wang C,
Gao S,
Jiang Y,
Khunsriraksakul C,
Otto JM,
Addison C,
Akiyama M
and 205 more — show all
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Nature · 2022 · PMID 36477530 · open access
Questions about rs4699726
What is rs4699726?
rs4699726 is a single position in the genome, in or near the near PCNAP1 gene. Published research associates it with drinks per week. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4699726 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4699726 come from?
GWAS Catalog, Nature 2022, PMID:36477530. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Drinks per week (rs4699726). MyGeneLog™. https://www.mygenelog.com/variants/rs4699726
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