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Mean volume of bilateral amygdala

NFKB1-AS1 · rs4698854

What the study found

Who was studied 18,575 European ancestry females.

The effect Each copy of the C allele shifted the measure 0.0654 higher (95% confidence interval 0.044-0.087); p = 3 × 10−9.

How common The C allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 4, band 4q24 — in an intron of NFKB1-AS1.

What each result means

C/C Two copies of the version the research linked to Mean volume of bilateral amygdala. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean volume of bilateral amygdala. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean volume of bilateral amygdala. This is the starting point the study compared everyone against.
Source

Questions about rs4698854

What is rs4698854?

rs4698854 is a single position in the genome, in or near the NFKB1-AS1 gene. Published research associates it with mean volume of bilateral amygdala. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4698854 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4698854 come from?

GWAS Catalog, Nature genetics 2025, PMID:40097784. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean volume of bilateral amygdala (rs4698854). MyGeneLog™. https://www.mygenelog.com/variants/rs4698854

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