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C-reactive protein levels or total cholesterol levels (pleiotropy)

ZNF644 · rs469772

Where this position leads

Condition: C-Reactive Protein Levels

rs469772 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs469772 rs469772 ZNF644

What the study found

Who was studied 65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol).

The effect The reported allele is T; the catalogue records no effect size ; p = 2 × 10−8.

Where it sits Chromosome 1, band 1p22.2 — between genes, 39.9 kb from RPL5P6.

What each result means

C/C No copy of the version the research linked to C-reactive protein levels or total cholesterol levels (pleiotropy). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to C-reactive protein levels or total cholesterol levels (pleiotropy). That is a smaller link than two copies.
T/T Two copies of the version the research linked to C-reactive protein levels or total cholesterol levels (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs469772

What is rs469772?

rs469772 is a single position in the genome, in or near the ZNF644 gene. Published research associates it with c-reactive protein levels or total cholesterol levels (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs469772 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs469772 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs469772 come from?

GWAS Catalog, BMC Genomics 2016, PMID:27286809. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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C-reactive protein levels or total cholesterol levels (pleiotropy) (rs469772). MyGeneLog™. https://www.mygenelog.com/variants/rs469772

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