Standard

Hexosylceramides (FA24:0) (Model 2)

CORIN · rs4695267

What the study found

Who was studied 7,126 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.227 lower; p = 5 × 10−35.

Where it sits Chromosome 4, band 4p12 — in an intron of CORIN.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Hexosylceramides (FA24:0) (Model 2) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hexosylceramides (FA24:0) (Model 2).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hexosylceramides (FA24:0) (Model 2) compared to the general population.
Source

Questions about rs4695267

What is rs4695267?

rs4695267 is a single position in the genome, in or near the CORIN gene. Published research associates it with hexosylceramides (fa24:0) (model 2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4695267 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4695267 come from?

GWAS Catalog, Nature communications 2026, PMID:42069741. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hexosylceramides (FA24:0) (Model 2) (rs4695267). MyGeneLog™. https://www.mygenelog.com/variants/rs4695267

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