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1-palmitoyl-2-oleoyl-GPI (16:0/18:1) levels

near HLMR1 · rs4683714

What the study found

Who was studied 8,809 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.134 higher (95% confidence interval 0.1-0.17); p = 6 × 10−16.

Where it sits Chromosome 3, band 3q23 — between genes, 2.6 kb from HLMR1.

What each result means

A/A Two copies of the version the research linked to 1-palmitoyl-2-oleoyl-GPI (16:0/18:1) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to 1-palmitoyl-2-oleoyl-GPI (16:0/18:1) levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to 1-palmitoyl-2-oleoyl-GPI (16:0/18:1) levels. This is the starting point the study compared everyone against.
Source

Questions about rs4683714

What is rs4683714?

rs4683714 is a single position in the genome, in or near the near HLMR1 gene. Published research associates it with 1-palmitoyl-2-oleoyl-gpi (16:0/18:1) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4683714 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4683714 come from?

GWAS Catalog, Metabolites 2022, PMID:35050183. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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1-palmitoyl-2-oleoyl-GPI (16:0/18:1) levels (rs4683714). MyGeneLog™. https://www.mygenelog.com/variants/rs4683714

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