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Total protein levels (UKB data field 30860)

near TLK1 · rs4668362

Where this position leads

Condition: Celiac Disease

rs4668362 Condition: Celiac Disease Celiac Disease Condition rs4668362 rs4668362 near TLK1

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0143 lower (95% confidence interval 0.01-0.019); p = 3 × 10−12.

How common The T allele had a frequency of about 59% in the people studied.

Where it sits Chromosome 2, band 2q31.1 — between genes, 10.2 kb from TLK1.

What each result means

G/G No copy of the version the research linked to Total protein levels (UKB data field 30860). This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Total protein levels (UKB data field 30860). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Total protein levels (UKB data field 30860). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4668362

What is rs4668362?

rs4668362 is a single position in the genome, in or near the near TLK1 gene. Published research associates it with total protein levels (ukb data field 30860). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4668362 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs4668362 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4668362 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total protein levels (UKB data field 30860) (rs4668362). MyGeneLog™. https://www.mygenelog.com/variants/rs4668362

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