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Triglycerides

GCKR · rs4665972

Where this position leads

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Triglycerides — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Triglycerides.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Triglycerides compared to the general population.

Source

Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations

Coram MA, Duan Q, Hoffmann TJ, Thornton T, Knowles JW, Johnson NA, Ochs-Balcom HM, Donlon TA, Martin LW, Eaton CB, Robinson JG, Risch NJ

and 5 more — show all

Zhu X, Kooperberg C, Li Y, Reiner AP, Tang H

American journal of human genetics · 2013 · PMID 23726366

Questions about rs4665972

What is rs4665972?

rs4665972 is a single position in the genome, in or near the GCKR gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4665972 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

Does having rs4665972 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4665972 come from?

GWAS Catalog, Am J Hum Genet 2013, PMID:23726366. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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