0 181122111Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others11Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,662 African American or Afro-Caribbean cases, 119,348 African American or Afro-Caribbean controls, 1,769 Hispanic or Latin American cases, 57,447 Hispanic or Latin American controls, 236 East Asian ancestry cases, 6,526 East Asian ancestry controls, 15,635 European ancestry cases, 429,252 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.228 higher (95% confidence interval 0.16-0.29); p = 4 × 10−16.
How common The T allele had a frequency of about 91% in the people studied.
Where it sits Chromosome 2, band 2q24.2 — in an intron of GCA.
What each result means
C/CNo copy of the version the research linked to Psoriasis vulgaris (PheCode 696.41). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Psoriasis vulgaris (PheCode 696.41). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Psoriasis vulgaris (PheCode 696.41). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs4664464
What is rs4664464?
rs4664464 is a single position in the genome, in or near the GCA gene. Published research associates it with psoriasis vulgaris (phecode 696.41). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4664464 linked to?
On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.
Does having rs4664464 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4664464 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 181122111Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others11Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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