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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 147,997 European ancestry cases, 575,269 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.0065 lower (95% confidence interval 0.0047-0.0083); p = 4 × 10−12.
How common The A allele had a frequency of about 43% in the people studied.
Where it sits Chromosome 1, band 1p34.1 — between genes, 3.2 kb from RPL6P1.
What each result means
A/ATwo copies of the version the research linked to Age-related hearing impairment. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Age-related hearing impairment. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Age-related hearing impairment. This is the starting point the study compared everyone against.
American journal of human genetics · 2022 · PMID 35580588 · open access
Questions about rs4660885
What is rs4660885?
rs4660885 is a single position in the genome, in or near the near RPL6P1 gene. Published research associates it with age-related hearing impairment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4660885 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4660885 come from?
GWAS Catalog, American journal of human genetics 2022, PMID:35580588. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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