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C-reactive protein levels or triglyceride levels (pleiotropy)

PABPC4 · rs4660808

Where this position leads

Condition: C-Reactive Protein Levels

rs4660808 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs4660808 rs4660808 PABPC4

What the study found

Who was studied 65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides).

The effect The reported allele is T; the catalogue records no effect size ; p = 2 × 10−13.

Where it sits Chromosome 1, band 1p34.3 — in an intron of PPIEL.

What each result means

C/C No copy of the version the research linked to C-reactive protein levels or triglyceride levels (pleiotropy). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to C-reactive protein levels or triglyceride levels (pleiotropy). That is a smaller link than two copies.
T/T Two copies of the version the research linked to C-reactive protein levels or triglyceride levels (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4660808

What is rs4660808?

rs4660808 is a single position in the genome, in or near the PABPC4 gene. Published research associates it with c-reactive protein levels or triglyceride levels (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4660808 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs4660808 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4660808 come from?

GWAS Catalog, BMC Genomics 2016, PMID:27286809. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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C-reactive protein levels or triglyceride levels (pleiotropy) (rs4660808). MyGeneLog™. https://www.mygenelog.com/variants/rs4660808

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