Standard
Hematology traits
DARC · rs4657616
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Hematology traits — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hematology traits.
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hematology traits compared to the general population.
Source
GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children
Li J,
Glessner JT,
Zhang H,
Hou C,
Wei Z,
Bradfield JP,
Mentch FD,
Guo Y,
Kim C,
Xia Q,
Chiavacci RM,
Thomas KA
and 5 more — show all
Human molecular genetics · 2013 · PMID 23263863
Questions about rs4657616
What is rs4657616?
rs4657616 is a single position in the genome, in or near the DARC gene. Published research associates it with hematology traits. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4657616 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4657616 come from?
GWAS Catalog, Hum Mol Genet 2012, PMID:23263863. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants