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Superior frontal gyrus grey matter volume

EIF4G3 · rs4654899

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Superior frontal gyrus grey matter volume compared to the general population.

A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Superior frontal gyrus grey matter volume.

C/C Published research associates this genotype with typical/baseline likelihood of Superior frontal gyrus grey matter volume — no copies of the reported risk allele.

Source

Common variants at 1p36 are associated with superior frontal gyrus volume

Hashimoto R, Ikeda M, Yamashita F, Ohi K, Yamamori H, Yasuda Y, Fujimoto M, Fukunaga M, Nemoto K, Takahashi T, Tochigi M, Onitsuka T

and 8 more — show all

Yamasue H, Matsuo K, Iidaka T, Iwata N, Suzuki M, Takeda M, Kasai K, Ozaki N

Translational psychiatry · 2014 · PMID 25335168 · open access

Questions about rs4654899

What is rs4654899?

rs4654899 is a single position in the genome, in or near the EIF4G3 gene. Published research associates it with superior frontal gyrus grey matter volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4654899 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4654899 come from?

GWAS Catalog, Transl Psychiatry 2014, PMID:25335168. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants